Jane married Isham Randolph on 25 Jul 1717 in Turkey Island, Henrico, Virginia, USA. Isham (son of William Randolph and Mary Isham) was born on 24 Feb 1685 in Turkey Island, Henrico, Virginia, USA; died on 02 Nov 1742. [Group Sheet] [Family Chart]

1. Jane Randolph was born on 09 Feb 1719; died on 31 Mar 1776.
2. Mary Randolph was born on 15 Oct 1725; died on 13 Oct 1803.
3. William Randolph was born in 1727; died on 27 Jun 1791 in Bristol, Gloucestershire, England.
4. Ann I Randolph was born in 1730; died in 1765 in Goochland, Virginia, USA.
5. Dorothea Randolph was born in 1732 in Goochland, Virginia, USA; died on 02 Feb 1794 in Dover, Goochland, Virginia, USA.
6. Susanna Randolph was born on 25 Sep 1738; died in 1806.